SCHEMBL838875

SCHEMBL838875

NC(Cc1cc(CP(=O)(O)O)cc(-c2cccc3ccccc23)c1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.72
▸ ALOX15 P16050 1/20 0.72
▸ CYP2C19 P33261 1/20 0.72
▸ KMT2A Q03164 1/20 0.72
▸ HSD17B10 Q99714 1/20 0.72
▸ TDP1 Q9NUW8 1/20 0.72
▸ MAPK1 P28482 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838874 1.00 MEN1 (0.72) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL30545232 1.00 MEN1 (0.72) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL2394195 0.84 MEN1 (1.00) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL29369964 0.84 MEN1 (1.00) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL2394204 0.84 MEN1 (1.00) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL1430608 0.83 MEN1 (0.73) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL794085 0.83 MEN1 (0.73) MEN1ALOX15CYP2C19KMT2AHSD17B10
Ammonia Solution, Strong SCHEMBL29580190 0.83 MEN1 (0.98) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL8923309 0.81 MEN1 (0.65) MEN1ALOX15CYP2C19KMT2AHSD17B10
SCHEMBL8923310 0.81 MEN1 (0.65) MEN1ALOX15CYP2C19KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5668121-A Glutamate (NMDA) receptor antagonists WARNER-LAMBERT COMPANY (US) 1997-09-16 — — US claimed
US-20260060932-A1 Encased Tamper Resistant Controlled Release Dosage Forms PURDUE PHARMA LP (US) 2026-03-05 — — US disclosed
US-20240238207-A1 Encased Tamper Resistant Controlled Release Dosage Forms PURDUE PHARMA LP (US) 2024-07-18 — — US disclosed
US-11911512-B2 Encased tamper resistant controlled release dosage forms PURDUE PHARMA L.P. (US) 2024-02-27 — — US disclosed
US-20230301921-A1 Encased Tamper Resistant Controlled Release Dosage Forms PURDUE PHARMA L.P. 2023-09-28 — — US disclosed
CN-104873455-B Coated Tamper Resistant Controlled Release Dosage Forms 普渡制药公司 2023-09-12 — — CN disclosed
US-11590082-B2 Encased tamper resistant controlled release dosage forms PURDUE PHARMA L.P. (US) 2023-02-28 — — US disclosed
US-20210251907-A1 Encased Tamper Resistant Controlled Release Dosage Forms PURDUE PHARMA L.P. 2021-08-19 — — US disclosed
US-10966932-B2 Encased tamper resistant controlled release dosage forms PURDUE PHARMA L.P. (US) 2021-04-06 — — US disclosed
US-20200121608-A1 Encased Tamper Resistant Controlled Release Dosage Forms PURDUE PHARMA LP (US) 2020-04-23 — — US disclosed
CN-1407884-A Controlled release hydrocodone formulations EURO CELTIQUE SA (LU) 2003-04-02 — — CN disclosed
US-20020192277-A1 Controlled release hydrocodone formulations PURDUE PHARMA L.P. 2002-12-19 — — US disclosed
EP-1227798-A1 CONTROLLED RELEASE HYDROCODONE FORMULATIONS Euro-Celtique S.A. (LU) 2002-08-07 — — EP disclosed
WO-2002036099-A1 CONTROLLED RELEASE HYDROCODONE FORMULATIONS EURO-CELTIQUE S.A. (LU) 2002-05-10 — — WO disclosed
WO-2000018378-A9 SUSTAINED RELEASE HYDROMORPHONE FORMULATIONS EXHIBITING BIMODAL CHARACTERISTICS EURO CELTIQUE SA (LU) 2001-07-19 — — WO disclosed
WO-2001032148-A1 CONTROLLED RELEASE HYDROCODONE FORMULATIONS EURO-CELTIQUE, S.A. (LU) 2001-05-10 — — WO disclosed
WO-2000018378-A1 SUSTAINED RELEASE HYDROMORPHONE FORMULATIONS EXHIBITING BIMODAL CHARACTERISTICS EURO-CELTIQUE, S.A. (LU) 2000-04-06 — — WO disclosed
US-5695751-A ADMINISTERING L-AMINO ACID OXIDASE TO REDUCE PLASMA LEVEL OF LARGE AMINO ACIDS TO ALLOW INCREASED TRANSPORT OF LARGE AMINO ACID DRUGS ACROSS BLOOD BRAIN BARRIER CORNELL RESEARCH FOUNDATION, INC. (US) 1997-12-09 — — US disclosed
US-5668121-A Glutamate (NMDA) receptor antagonists WARNER-LAMBERT COMPANY (US) 1997-09-16 — — US disclosed
US-5489717-A Glutamate (NMDA) receptor antagonists WARNER-LAMBERT COMPANY 1996-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060932-A1 Encased Tamper Resistant Controlled Release Dosage Forms OGFR, OPRM1, OPRK1 MEN1 4797/4885ALOX15 2353/4885CYP2C19 188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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