Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 7/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.46 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | GNPAT | O15228 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923350 | 1.00 | HDAC1 (0.51) | HDAC1HDAC4HDAC6CTSLCTSS | |
| SCHEMBL8691098 | 0.91 | CTSL (0.49) | HDAC1HDAC4HDAC6CTSLCTSS | |
| SCHEMBL8922671 | 0.88 | HDAC1 (0.55) | HDAC1HDAC4HDAC6CTSLCTSS | |
| SCHEMBL8922675 | 0.88 | HDAC1 (0.55) | HDAC1HDAC4HDAC6CTSLCTSS | |
| SCHEMBL6891565 | 0.88 | CTSL (0.48) | HDAC1HDAC4HDAC6CTSLCTSS | |
| SCHEMBL4031334 | 0.87 | HDAC4 (0.52) | HDAC1HDAC4HDAC6CTSLCTSS | |
| SCHEMBL6897252 | 0.87 | HDAC4 (0.52) | HDAC1HDAC4HDAC6CTSLCTSS | |
| SCHEMBL4031337 | 0.87 | HDAC4 (0.52) | HDAC1HDAC4HDAC6CTSLCTSS | |
| SCHEMBL8921345 | 0.86 | HDAC4 (0.51) | HDAC1HDAC4HDAC6CTSLCTSS | |
| SCHEMBL8921335 | 0.86 | HDAC4 (0.51) | HDAC1HDAC4HDAC6CTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627278-A | MULTISTAGE REACTION FORMED BY AMIDATION, COUPLING AND REDUCTION | BRISTOL-MYERS SQUIBB CO. (US) | 1997-05-06 | — | — | US | claimed |