Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | SNCA | P37840 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.51 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.51 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29857297 | 0.94 | SNCA (0.65) | TSHRSMN1; SMN2SNCALMNAL3MBTL1 | |
| SCHEMBL28275730 | 0.94 | SNCA (0.65) | TSHRSMN1; SMN2SNCALMNAL3MBTL1 | |
| SCHEMBL29357423 | 0.94 | SNCA (0.65) | TSHRSMN1; SMN2SNCALMNAL3MBTL1 | |
| SCHEMBL1556 | 0.94 | SNCA (0.65) | TSHRSMN1; SMN2SNCALMNAL3MBTL1 | |
| SCHEMBL304050 | 0.94 | SNCA (0.65) | TSHRSMN1; SMN2SNCALMNAL3MBTL1 | |
| Naphthalene SCHEMBL28216326 | 0.94 | SNCA (0.65) | TSHRSMN1; SMN2SNCALMNAL3MBTL1 | |
| Bicarbonate SCHEMBL7292653 | 0.92 | SNCA (0.64) | TSHRSMN1; SMN2SNCALMNAL3MBTL1 | |
| SCHEMBL9888352 | 0.92 | SNCA (0.62) | TSHRSMN1; SMN2SNCALMNAL3MBTL1 | |
| Sulfuric Acid SCHEMBL7067030 | 0.92 | SNCA (0.62) | TSHRSMN1; SMN2SNCALMNAL3MBTL1 | |
| SCHEMBL1177404 | 0.92 | SNCA (0.62) | TSHRSMN1; SMN2SNCALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665886-A | Salts of substituted nitrogenous heteroaromatic compounds, a process for their preparation and pharmaceutical compositions containing them | SANOFI (FR) | 1997-09-09 | — | — | US | disclosed |