Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.55 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28275730 | 0.98 | SNCA (0.65) | SNCALMNAL3MBTL1F2PRSS1 | |
| SCHEMBL304050 | 0.98 | SNCA (0.65) | SNCALMNAL3MBTL1F2PRSS1 | |
| Naphthalene SCHEMBL28216326 | 0.98 | SNCA (0.65) | SNCALMNAL3MBTL1F2PRSS1 | |
| SCHEMBL29357423 | 0.98 | SNCA (0.65) | SNCALMNAL3MBTL1F2PRSS1 | |
| SCHEMBL1556 | 0.98 | SNCA (0.65) | SNCALMNAL3MBTL1F2PRSS1 | |
| SCHEMBL29857297 | 0.98 | SNCA (0.65) | SNCALMNAL3MBTL1F2PRSS1 | |
| SCHEMBL1589609 | 0.96 | SNCA (0.62) | SNCALMNAL3MBTL1F2PRSS1 | |
| Sulfuric Acid SCHEMBL7067030 | 0.96 | SNCA (0.62) | SNCALMNAL3MBTL1F2PRSS1 | |
| SCHEMBL1588808 | 0.96 | SNCA (0.62) | SNCALMNAL3MBTL1F2PRSS1 | |
| Hydrochloric Acid SCHEMBL3441755 | 0.96 | SNCA (0.62) | SNCALMNAL3MBTL1F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8692014-B2 | Acid addition salts of 5-aminolevulinic acid or its derivatives | PHOTOCURE ASA (NO) | 2014-04-08 | — | — | US | disclosed |
| US-20110125012-A1 | ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES | BRAENDEN JON ERIK | 2011-05-26 | — | — | US | disclosed |
| EP-2308830-A1 | Acid addition salts of 5-aminolevulinic acid or its derivatives | Photocure ASA (NO) | 2011-04-13 | — | — | EP | disclosed |
| US-7888526-B2 | Nonhygroscopic photosensitizing agents; sulphonate, hydrobromide, sulfate, nitrate and/or phosphate derivatives; diagnosing skin disorders | PHOTOCURE ASA (NO) | 2011-02-15 | — | — | US | disclosed |
| US-20080064752-A1 | Acid Addition Salts Of-5-Aminolevulinic Acid Or Its Derivatives | PHOTOCURE ASA (NO) | 2008-03-13 | — | — | US | disclosed |
| EP-1727786-A1 | ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES | Photocure ASA (NO) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005092838-A1 | ACID ADDITION SALTS OF 5-AMINOLEVULINIC ACID OR ITS DERIVATIVES | PHOTOCURE ASA (NO) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064752-A1 | Acid Addition Salts Of-5-Aminolevulinic Acid Or Its Derivatives | ALAD, AASDHPPT, ABAT | SNCA 1492/4885LMNA 3222/4885L3MBTL1 2982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.