Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8920913 | 0.91 | CCKBR (0.60) | CCKBR | |
| SCHEMBL8920338 | 0.91 | CCKBR (0.50) | CCKBR | |
| SCHEMBL8922705 | 0.90 | CCKBR (0.55) | CCKBR | |
| SCHEMBL8922441 | 0.89 | CCKBR (0.51) | CCKBRGRIN2B | |
| SCHEMBL8919350 | 0.89 | CCKBR (0.65) | CCKBR | |
| SCHEMBL8919641 | 0.88 | CCKBR (0.53) | CCKBR | |
| SCHEMBL8919276 | 0.88 | CCKBR (0.54) | CCKBR | |
| SCHEMBL8922358 | 0.87 | CCKBR (0.53) | CCKBR | |
| SCHEMBL8921287 | 0.87 | CCKBR (0.68) | CCKBR | |
| SCHEMBL8922639 | 0.87 | CCKBR (0.69) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643904-A | Substituted hexahdryoazepinones and tetrahydrobenzazepinones | PFIZER INC. (US) | 1997-07-01 | — | — | US | disclosed |
| US-5484917-A | FOR TREATMENT AND PREVENTION OF GASTROINTESTINAL DISORDERS, PAIN AND ANXIETY | PFIZER INC. (US) | 1996-01-16 | — | — | US | disclosed |