Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.32 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694624 | 1.00 | ALDH1A1 (0.35) | ALDH1A1MAPTDPP8DPP9GAA | |
| SCHEMBL8925242 | 0.91 | ALDH1A1 (0.34) | ALDH1A1MAPTDPP8DPP9GAA | |
| SCHEMBL8694613 | 0.91 | ALDH1A1 (0.34) | ALDH1A1MAPTDPP8DPP9GAA | |
| SCHEMBL8924553 | 0.90 | ALDH1A1 (0.33) | ALDH1A1MAPTDPP8DPP9GAA | |
| SCHEMBL8696193 | 0.88 | GAA (0.38) | ALDH1A1MAPTGAAHTR2AHPGD | |
| SCHEMBL9393713 | 0.88 | GAA (0.38) | ALDH1A1MAPTGAAHTR2AHPGD | |
| SCHEMBL8924299 | 0.87 | MAPT (0.37) | ALDH1A1MAPTGAAHTR2AHPGD | |
| SCHEMBL8694953 | 0.87 | MAPT (0.37) | ALDH1A1MAPTGAAHTR2AHPGD | |
| SCHEMBL8923969 | 0.87 | ALDH1A1 (0.37) | ALDH1A1MAPTHTR2AHPGDNPC1 | |
| SCHEMBL8693099 | 0.87 | ALDH1A1 (0.37) | ALDH1A1MAPTHTR2AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641770-A | THIENAMYCINS ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1997-06-24 | — | — | US | disclosed |
| WO-1994014811-A1 | 2-(2-SUBSTITUTED PYRROLIDIN-4-YL)THIO-CARBAPENEM DERIVATIVES | CHONG KUN DANG CORP. (KR) | 1994-07-07 | — | — | WO | disclosed |