Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3682772 | 0.88 | TSHR (0.53) | TSHRTHRBALDH1A1PRKCA | |
| 1,4-Butanediol SCHEMBL18173955 | 0.87 | TSHR (0.49) | TSHRTHRBALDH1A1PRKCA | |
| SCHEMBL27370383 | 0.86 | TSHR (0.56) | TSHRTHRBALDH1A1PRKCA | |
| SCHEMBL730808 | 0.86 | TSHR (0.56) | TSHRTHRBALDH1A1PRKCA | |
| SCHEMBL27370412 | 0.86 | TSHR (0.56) | TSHRTHRBALDH1A1PRKCA | |
| SCHEMBL730544 | 0.86 | TSHR (0.56) | TSHRTHRBALDH1A1PRKCA | |
| SCHEMBL8581536 | 0.86 | TSHR (0.47) | TSHRTHRBALDH1A1PRKCAPOLB | |
| SCHEMBL22207427 | 0.86 | TSHR (0.56) | TSHRTHRBALDH1A1PRKCA | |
| SCHEMBL27370395 | 0.86 | TSHR (0.56) | TSHRTHRBALDH1A1PRKCA | |
| SCHEMBL730445 | 0.85 | TSHR (0.50) | TSHRTHRBALDH1A1PRKCATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591563-A | POLYACRYLATED DIURETHANE, ACRYLOYLMORPHOLINE | TAKEMOTO YUSHI KABUSHIKI KAISHA (JP) | 1997-01-07 | — | — | US | disclosed |