Biphenyl

Biphenyl

SCHEMBL8924102

COC.NO.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.56
TAAR1 Q96RJ0 2/20 0.48
CYP3A4 P08684 1/20 0.48
HSD17B10 Q99714 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
MMP3 P08254 1/20 0.48
BCL2L1 Q07817 1/20 0.48
PDE4B Q07343 2/20 0.44
PDE4A P27815 1/20 0.44
PDE4C Q08493 1/20 0.44
PDE4D Q08499 1/20 0.44
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
WDR5 P61964 1/20 0.44
SLC22A2 O15244 1/20 0.43
SLC22A1 O15245 1/20 0.43
SLC22A3 O75751 1/20 0.43
SLC6A4 P31645 1/20 0.43
CA4 P22748 1/20 0.43
ABCC4 O15439 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28881047 0.90 ALDH1A1 (0.69) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL3908169 0.90 ALDH1A1 (0.69) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL18139126 0.87 ALDH1A1 (0.64) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL6427852 0.87 ALDH1A1 (0.75) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL10583472 0.84 ALDH1A1 (0.60) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL27351438 0.83 ALDH1A1 (0.69) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL1495102 0.82 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1MMP3BCL2L1
Biphenyl SCHEMBL9139034 0.80 ALDH1A1 (0.64) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL1133504 0.79 ALDH1A1 (0.75) ALDH1A1TAAR1CYP3A4HSD17B10TDP1
Biphenyl SCHEMBL1557083 0.79 ALDH1A1 (0.75) ALDH1A1TAAR1CYP3A4HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5625067-A Cyclopentane ether derivatives, processes for their production, and their pharmaceutical use SCHERING AKTIENGESELLSCHAFT (DE) 1997-04-29 US disclosed