Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 17/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7494469 | 0.94 | GSK3B (0.46) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL8922989 | 0.94 | MEN1 (0.51) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL9212277 | 0.90 | CACNA1F (0.40) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL8851756 | 0.90 | MEN1 (0.42) | CACNA1FPOLBMAPK1CACNA1DKCNH2 | |
| SCHEMBL7836509 | 0.86 | KCNH2 (0.46) | POLBKCNH2MEN1KMT2ATOP2A | |
| SCHEMBL7846922 | 0.86 | KCNH2 (0.46) | POLBKCNH2MEN1KMT2ATOP2A | |
| SCHEMBL7836504 | 0.86 | KCNH2 (0.46) | POLBKCNH2MEN1KMT2ATOP2A | |
| SCHEMBL7494366 | 0.86 | KCNH2 (0.46) | POLBKCNH2MEN1KMT2ATOP2A | |
| SCHEMBL7846924 | 0.86 | KCNH2 (0.46) | POLBKCNH2MEN1KMT2ATOP2A | |
| Hydrochloric Acid SCHEMBL8925488 | 0.85 | KCNH2 (0.59) | CACNA1FPOLBMAPK1CACNA1DKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5621105-A | REACTING HALO-SUBSTITUTED QUINOLONECARBOXYLIC ACID OR NAPHTHYRIDONECARBOXYLIC ACID WITH 1-AMINOMETHYL-2-OXA-7-AZABICYCLO/3.3.0/OCTANE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| US-5574161-A | GRAMPOSITIVE BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-12 | — | — | US | disclosed |
| EP-0589318-B1 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| US-5395944-A | Bactericides | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
| EP-0589318-A2 | Antibacterial 7-(aminomethyl-oxa-7-azabicyclo(3.3.0)oct-7-yl)quinolone- and -naphthyridonecarboxylic acid derivatives | BAYER AG (DE) | 1994-03-30 | — | — | EP | disclosed |