Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4850585 | 0.90 | CYP1A2 (0.56) | HSP90AB1TDP1NPC1RAB9ACYP1A2 | |
| SCHEMBL31012122 | 0.90 | CYP1A2 (0.56) | HSP90AB1TDP1NPC1RAB9ACYP1A2 | |
| SCHEMBL31065555 | 0.90 | IDO1 (0.46) | TSHRKDM4EL3MBTL1HSP90AB1TDP1 | |
| SCHEMBL257599 | 0.86 | KCNH2 (0.50) | TSHRL3MBTL1HSP90AB1LMNACYP1A2 | |
| Hydroxyamine SCHEMBL8924246 | 0.84 | MEN1 (0.53) | HSP90AB1TDP1HTTCYP1A2CYP2C19 | |
| SCHEMBL21822350 | 0.83 | TSHR (0.56) | TSHRKDM4EL3MBTL1TDP1NPC1 | |
| SCHEMBL1578240 | 0.82 | KEAP1 (0.49) | TSHRFFAR1AKR1B1 | |
| SCHEMBL10269557 | 0.82 | FFAR1 (0.43) | KDM4EL3MBTL1HSP90AB1TDP1FFAR1 | |
| SCHEMBL21822314 | 0.81 | TSHR (0.54) | TSHRKDM4EL3MBTL1TDP1NPC1 | |
| 1-Naphthol SCHEMBL9673700 | 0.79 | CYP1A2 (0.63) | TSHRKDM4EL3MBTL1TDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486745-A1 | Improved solvents for chromogens useful in the manufacture of carbonless copying paper | MONSANTO EUROPE S.A./N.V. (BE) | 1992-05-27 | — | — | EP | disclosed |