Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SNCA | P37840 | 1/20 | 0.54 |
| ▸ | HPSE | Q9Y251 | 3/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9002412 | 0.90 | ESR1 (0.56) | ESR1ESR2GAAL3MBTL1MAPT | |
| SCHEMBL17265011 | 0.88 | KDM6B (0.60) | ESR1ESR2GAAMAPTHDAC6 | |
| SCHEMBL4216490 | 0.88 | RAB9A (0.55) | ESR1ESR2GAAL3MBTL1MAPT | |
| SCHEMBL3317791 | 0.85 | KDM6B (0.63) | ESR1ESR2GAAMAPTSNCA | |
| SCHEMBL13866524 | 0.85 | ESR1 (0.60) | ESR1ESR2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7905531 | 0.85 | SMN1; SMN2 (0.70) | ESR1ESR2GAAL3MBTL1MAPT | |
| SCHEMBL2244575 | 0.85 | SMN1; SMN2 (0.70) | ESR1ESR2GAAL3MBTL1MAPT | |
| SCHEMBL13528498 | 0.83 | NPC1 (0.72) | ESR1ESR2GAAL3MBTL1MAPT | |
| SCHEMBL9293285 | 0.82 | HDAC6 (0.58) | ESR1ESR2GAAL3MBTL1HPSE | |
| SCHEMBL12408920 | 0.82 | GAA (0.59) | ESR1ESR2GAAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298189-A | Fluorescent compound dispersed in polymer matrix, no self-absorption, stable to high energy radiation | NANOPTICS INCORPORATED (US) | 1994-03-29 | — | — | US | claimed |
| US-5606638-A | Organic scintillator systems and optical fibers containing polycyclic aromatic compounds | NANOPTICS INCORPORATED (US) | 1997-02-25 | — | — | US | disclosed |
| US-5298189-A | Fluorescent compound dispersed in polymer matrix, no self-absorption, stable to high energy radiation | NANOPTICS INCORPORATED (US) | 1994-03-29 | — | — | US | disclosed |