Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8694252 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CCR5MAPTHPGDTDP1 | |
| SCHEMBL8695031 | 0.93 | ALDH1A1 (0.37) | ALDH1A1CCR5MAPTHPGDTDP1 | |
| SCHEMBL8923996 | 0.93 | ALDH1A1 (0.37) | ALDH1A1CCR5MAPTHPGDTDP1 | |
| SCHEMBL9388492 | 0.89 | ALDH1A1 (0.37) | ALDH1A1CCR5MAPTHPGDTDP1 | |
| SCHEMBL8690847 | 0.89 | ALDH1A1 (0.37) | ALDH1A1CCR5MAPTHPGDTDP1 | |
| SCHEMBL8924025 | 0.89 | ALDH1A1 (0.35) | ALDH1A1CCR5MAPTHPGDTDP1 | |
| SCHEMBL8689886 | 0.89 | ALDH1A1 (0.35) | ALDH1A1CCR5MAPTHPGDTDP1 | |
| SCHEMBL8694749 | 0.88 | ALDH1A1 (0.37) | ALDH1A1CCR5MAPTHPGDTDP1 | |
| SCHEMBL8693508 | 0.88 | ALDH1A1 (0.37) | ALDH1A1CCR5MAPTHPGDTDP1 | |
| SCHEMBL9519504 | 0.86 | ALDH1A1 (0.37) | ALDH1A1CCR5MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5641770-A | THIENAMYCINS ANTIBIOTICS | CHONG KUN DANG CORP. (KR) | 1997-06-24 | — | — | US | disclosed |
| WO-1994014811-A1 | 2-(2-SUBSTITUTED PYRROLIDIN-4-YL)THIO-CARBAPENEM DERIVATIVES | CHONG KUN DANG CORP. (KR) | 1994-07-07 | — | — | WO | disclosed |