SCHEMBL8924405

SCHEMBL8924405

COC(=O)C(CN)c1ccc2c(c1)c(CC(N)=O)c(C)n2Cc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8924570 0.90 PLA2G2A (0.68) PLA2G2A
SCHEMBL8926960 0.88 PLA2G2A (0.60) PLA2G2A
SCHEMBL8924410 0.83 PLA2G2A (0.66) PLA2G2A
SCHEMBL8926148 0.82 PLA2G2A (0.66) PLA2G2A
SCHEMBL8925297 0.82 PLA2G2A (0.60) PLA2G2A
SCHEMBL8924915 0.82 PLA2G2A (0.64) PLA2G2A
SCHEMBL8925179 0.81 PLA2G2A (0.63) PLA2G2A
SCHEMBL8926972 0.80 PLA2G2A (0.62) PLA2G2A
SCHEMBL8924411 0.80 PLA2G2A (0.62) PLA2G2A
SCHEMBL7953243 0.79 PLA2G2A (1.00) PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5684034-A INHIBITORS OF HUMAN NON-PANCREATIC SECRETORY PHOSPHOLIPASE A2, TREATMENT OF SEPTIC SHOCK, TRAUMA, RESPIRATORY DISORDERS, RHEUMATIC ARTHRITIS, INHIBITORS OF ARACHIDONIC ACID RELEASE ELI LILLY AND COMPANY (US) 1997-11-04 US disclosed