Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984359 | 0.81 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8644375 | 0.79 | HTR1D (0.78) | HTR1DHTR1B | |
| SCHEMBL8924517 | 0.78 | HTR1D (0.81) | HTR1DHTR1B | |
| SCHEMBL8984430 | 0.78 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL8923743 | 0.78 | HTR1D (0.82) | HTR1DHTR1B | |
| SCHEMBL7476048 | 0.77 | HTR1D (0.70) | HTR1DHTR1B | |
| SCHEMBL7476126 | 0.77 | HTR1D (0.77) | HTR1DHTR1B | |
| SCHEMBL7474121 | 0.77 | HTR1D (0.77) | HTR1DHTR1B | |
| SCHEMBL7474899 | 0.77 | HTR1D (0.88) | HTR1DHTR1B | |
| SCHEMBL7475794 | 0.77 | HTR1D (0.76) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614524-A | Piperazine derivatives as 5-HT1 Agonists | MERCK SHARP & DOHME LTD. (GB) | 1997-03-25 | — | — | US | claimed |
| US-5614524-A | Piperazine derivatives as 5-HT1 Agonists | MERCK SHARP & DOHME LTD. (GB) | 1997-03-25 | — | — | US | disclosed |