Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 4/20 | 0.47 |
| ▸ | GABRD | O14764 | 4/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.47 |
| ▸ | GABRE | P78334 | 4/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.35 |
| ▸ | KDM4A | O75164 | 4/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1551487 | 0.83 | MKNK1 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8924569 | 0.77 | GABRP (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6196417 | 0.75 | GABRP (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8562355 | 0.69 | — | — | |
| SCHEMBL6698056 | 0.67 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL26933995 | 0.64 | — | — | |
| SCHEMBL30705741 | 0.64 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL220538 | 0.64 | GABRP (1.00) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| Hydrochloric Acid SCHEMBL22797869 | 0.62 | GABRP (0.96) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3278665 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |