Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.46 |
| ▸ | CDC25A | P30304 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 2/20 | 0.46 |
| ▸ | CDC25C | P30307 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8923717 | 0.79 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL6194685 | 0.79 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DMAPT | |
| Hydrochloric Acid SCHEMBL6196997 | 0.79 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL6200825 | 0.78 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DMAPT | |
| Iodide SCHEMBL8924762 | 0.76 | CDC25A (0.52) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7491504 | 0.76 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL6199824 | 0.76 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL8923403 | 0.76 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4DMAPT | |
| Hydrochloric Acid SCHEMBL6199487 | 0.75 | SREBF2 (0.59) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL6201319 | 0.75 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |