Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | ABCG2 | Q9UNQ0 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924620 | 1.00 | TYR (0.53) | TYRCA12CA1CA2CA7 | |
| SCHEMBL8924627 | 1.00 | TYR (0.53) | TYRCA12CA1CA2CA7 | |
| SCHEMBL8921211 | 0.86 | LMNA (0.54) | ABCG2MAPTALDH1A1KDM4EMAOB | |
| SCHEMBL8921219 | 0.86 | LMNA (0.54) | ABCG2MAPTALDH1A1KDM4EMAOB | |
| SCHEMBL8921206 | 0.86 | LMNA (0.54) | ABCG2MAPTALDH1A1KDM4EMAOB | |
| SCHEMBL8923348 | 0.85 | HDAC2 (0.49) | ABCG2MAPTALDH1A1PKMMAOB | |
| SCHEMBL8923356 | 0.85 | HDAC2 (0.49) | ABCG2MAPTALDH1A1PKMMAOB | |
| SCHEMBL8923336 | 0.85 | HDAC2 (0.49) | ABCG2MAPTALDH1A1PKMMAOB | |
| SCHEMBL8919810 | 0.83 | CCNB2 (0.54) | KDM4EMMP2MMP9MMP1P4HB | |
| SCHEMBL8923693 | 0.83 | APP (0.59) | MAPTAPPMMP9MAOBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802897-A1 | NOVEL COMPOUNDS | Smithkline Beecham S.p.A. (IT) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021638-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM S.P.A. (IT) | 1996-07-18 | — | — | WO | disclosed |