Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613159 | 0.93 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPTSOAT1EGLN1 | |
| SCHEMBL35720 | 0.93 | — | — | |
| Methacrylic Acid SCHEMBL28303868 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTSOAT1EGLN1 | |
| Propionic Acid SCHEMBL11418925 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTSOAT1EGLN1 | |
| Acetic Acid SCHEMBL29279683 | 0.91 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTSOAT1EGLN1 | |
| Methyl Alcohol SCHEMBL29084611 | 0.91 | ALDH1A1 (0.50) | ALDH1A1TSHRMAPTSOAT1EGLN1 | |
| Malonic Acid SCHEMBL3867309 | 0.87 | EGLN1 (0.47) | ALDH1A1TSHRMAPTSOAT1EGLN1 | |
| Succinic Acid SCHEMBL3872447 | 0.87 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPTSOAT1EGLN1 | |
| Dimethylamine SCHEMBL444411 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTSOAT1EGLN1 | |
| Ethylene Glycol SCHEMBL1533845 | 0.86 | ALDH1A1 (0.47) | ALDH1A1TSHRMAPTSOAT1EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663032-A | NAPHTHOL DERIVATIVE REDUCING AGENT | CANON KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0653680-A2 | Photosensitive composition, photosensitive material and image forming method | CANON KABUSHIKI KAISHA (JP) | 1995-05-17 | — | — | EP | disclosed |