Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18168008 | 0.82 | KDM4E (0.50) | IRAK4ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL28303005 | 0.76 | CYP2A6 (0.47) | ALDH1A1MAPTKDM4EPOLBMEN1 | |
| SCHEMBL28712036 | 0.74 | KDM4E (0.52) | KDM4EPOLBKMT2APTPN1 | |
| SCHEMBL5769923 | 0.72 | CYP2A6 (0.41) | ALDH1A1MAPTKDM4EPOLBMEN1 | |
| SCHEMBL14376686 | 0.71 | MAPT (0.58) | ALDH1A1MAPTKDM4EPOLBMEN1 | |
| SCHEMBL16419707 | 0.71 | IRAK4 (0.38) | IRAK4ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL20187481 | 0.70 | MAPT (0.34) | ALDH1A1MAPTKDM4EPOLBMEN1 | |
| SCHEMBL20209382 | 0.69 | MAPT (0.33) | MAPTKDM4EPOLBHTTSMN1; SMN2 | |
| SCHEMBL8923789 | 0.69 | HSD17B14 (0.53) | ALDH1A1KDM4E | |
| SCHEMBL8925427 | 0.69 | GSK3B (0.52) | IRAK4ALDH1A1KDM4EKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |