Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.57 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.50 |
| ▸ | TACR2 | P21452 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684658 | 0.94 | CA2 (0.57) | CA2ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL27284647 | 0.86 | CA2 (0.58) | CA2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27612462 | 0.86 | CA2 (0.58) | CA2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27286821 | 0.86 | CA2 (0.58) | CA2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9220491 | 0.86 | CA2 (0.58) | CA2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9214262 | 0.86 | CA2 (0.58) | CA2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL28753622 | 0.86 | CA2 (0.58) | CA2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL8924808 | 0.86 | CA2 (0.58) | CA2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL9222801 | 0.86 | CA2 (0.58) | CA2ESR1ADRA2AADORA3TACR2 | |
| SCHEMBL27283685 | 0.86 | CA2 (0.58) | CA2ESR1ADRA2AADORA3TACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |