Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924520 | 0.91 | PLA2G2A (0.60) | PLA2G2A | |
| SCHEMBL8926187 | 0.91 | PLA2G2A (0.62) | PLA2G2A | |
| SCHEMBL8926960 | 0.86 | PLA2G2A (0.60) | PLA2G2A | |
| SCHEMBL8925297 | 0.84 | PLA2G2A (0.60) | PLA2G2A | |
| SCHEMBL8924411 | 0.84 | PLA2G2A (0.62) | PLA2G2A | |
| SCHEMBL8924449 | 0.83 | PLA2G2A (0.64) | PLA2G2A | |
| SCHEMBL8924525 | 0.80 | PLA2G2A (0.68) | PLA2G2A | |
| SCHEMBL8924850 | 0.80 | PLA2G2A (0.72) | PLA2G2A | |
| SCHEMBL8924862 | 0.78 | PLA2G2A (0.69) | PLA2G2A | |
| SCHEMBL8924528 | 0.77 | PLA2G2A (0.71) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684034-A | INHIBITORS OF HUMAN NON-PANCREATIC SECRETORY PHOSPHOLIPASE A2, TREATMENT OF SEPTIC SHOCK, TRAUMA, RESPIRATORY DISORDERS, RHEUMATIC ARTHRITIS, INHIBITORS OF ARACHIDONIC ACID RELEASE | ELI LILLY AND COMPANY (US) | 1997-11-04 | — | — | US | disclosed |