Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | BRS3 | P32247 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168949 | 1.00 | PTPN11 (0.51) | PTPN11ALDH1A1XDHPDE4APDE4B | |
| SCHEMBL7168950 | 1.00 | PTPN11 (0.51) | PTPN11ALDH1A1XDHPDE4APDE4B | |
| SCHEMBL7165175 | 1.00 | PTPN11 (0.51) | PTPN11ALDH1A1XDHPDE4APDE4B | |
| SCHEMBL7165171 | 1.00 | PTPN11 (0.51) | PTPN11ALDH1A1XDHPDE4APDE4B | |
| SCHEMBL8922483 | 0.96 | PTPN11 (0.55) | PTPN11ALDH1A1XDHPDE4APDE4B | |
| SCHEMBL6421561 | 0.96 | PTPN11 (0.55) | PTPN11ALDH1A1XDHPDE4APDE4B | |
| SCHEMBL3195027 | 0.96 | PTPN11 (0.55) | PTPN11ALDH1A1XDHPDE4APDE4B | |
| SCHEMBL7188692 | 0.88 | XDH (0.44) | ALDH1A1XDHPDE4APDE4BPDE4C | |
| SCHEMBL8924907 | 0.88 | PDE4A (0.47) | PTPN11ALDH1A1XDHPDE4APDE4B | |
| SCHEMBL8176758 | 0.86 | PDE4A (0.51) | PTPN11ALDH1A1XDHPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658493-A | Ferroelectric liquid crystals for nonlinear optics applications | UNIVERSITY RESEARCH CORPORATION (US) | 1997-08-19 | — | — | US | disclosed |
| US-5637256-A | Ferroelectric liquid crystals for nonlinear optics applications | UNIVERSITY RESEARCH CORPORATION (US) | 1997-06-10 | — | — | US | disclosed |
| US-5543078-A | A CHIRAL NONRACEMIC COMPOUND | UNIVERSITY RESEARCH CORPORATION (US) | 1996-08-06 | — | — | US | disclosed |
| WO-1992020058-A2 | FERROELECTRIC LIQUID CRYSTALS FOR NONLINEAR OPTICS APPLICATIONS | UNIVERSITY RESEARCH CORPORATION (US) | 1992-11-12 | — | — | WO | disclosed |