SCHEMBL8925288

SCHEMBL8925288

CCCCCCCC(O)Oc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 3/20 0.49
ABCB1 P08183 1/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
PLA2G4B P0C869 2/20 0.45
ALDH1A1 P00352 2/20 0.45
SRD5A2 P31213 1/20 0.44
CTRC Q99895 1/20 0.44
BDKRB2 P30411 1/20 0.43
PPARA Q07869 1/20 0.43
PRSS1 P07477 1/20 0.43
CTSG P08311 1/20 0.43
CTRB1 P17538 1/20 0.43
CMA1 P23946 1/20 0.43
GAA P10253 2/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
LMNA P02545 1/20 0.43
MAPK1 P28482 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27868074 1.00 ELANE (0.49) ELANEABCB1TP53TSHRPLA2G4B
SCHEMBL18264279 1.00 ELANE (0.49) ELANEABCB1TP53TSHRPLA2G4B
SCHEMBL8371946 0.87 ELANE (0.50) ELANEABCB1TP53TSHRPLA2G4B
SCHEMBL27677830 0.87 GAA (0.51) ELANEABCB1ALDH1A1SRD5A2PPARA
SCHEMBL7611800 0.87 ELANE (0.50) ELANEABCB1TP53TSHRPLA2G4B
SCHEMBL27475535 0.87 GAA (0.51) ELANEABCB1ALDH1A1SRD5A2PPARA
SCHEMBL8375161 0.87 ELANE (0.50) ELANEABCB1TP53TSHRPLA2G4B
SCHEMBL9061631 0.87 TP53 (0.60) TP53TSHRPLA2G4BALDH1A1MAPT
SCHEMBL28629364 0.86 ALDH1A1 (0.51) ELANEABCB1TP53TSHRPLA2G4B
SCHEMBL3626125 0.85 TP53 (0.58) TP53TSHRPLA2G4BMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5601756-A SUBSTITUTED BENZOPHENONE COMPOUNDS LYCUS LTD. 1997-02-11 US disclosed
EP-0020613-A4 PHOTOCURABLE ACRYLIC COATED POLYCARBONATE ARTICLES. GEN ELECTRIC (US) 1981-03-24 EP disclosed
EP-0020613-A1 PHOTOCURABLE ACRYLIC COATED POLYCARBONATE ARTICLES GENERAL ELECTRIC COMPANY (US) 1981-01-07 EP disclosed
WO-1980000968-A1 PHOTOCURABLE ACRYLIC COATED POLYCARBONATE ARTICLES GEN ELECTRIC (US) 1980-05-15 WO disclosed
US-4198465-A WEAR AND CHEMICAL RESISTANT GENERAL ELECTRIC COMPANY (US) 1980-04-15 US disclosed