Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352281 | 0.69 | GAA (1.00) | GAAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL8924730 | 0.67 | SLC6A2 (0.33) | — | |
| SCHEMBL2066585 | 0.66 | KDM4E (0.34) | GAAKDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL18390096 | 0.66 | GAA (0.59) | GAAKDM4EGLAALDH1A1LMNA | |
| SCHEMBL31341343 | 0.66 | GAA (0.90) | GAAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL11131278 | 0.64 | KDM4E (0.58) | GAAKDM4EGLAALDH1A1LMNA | |
| SCHEMBL13181514 | 0.64 | GAA (0.52) | GAAKDM4EGLAPOLBALDH1A1 | |
| SCHEMBL18390275 | 0.64 | GAA (0.60) | GAAKDM4EGLAALDH1A1LMNA | |
| SCHEMBL18390892 | 0.64 | GAA (0.71) | GAAKDM4EMAPTTSHR | |
| SCHEMBL18390893 | 0.64 | GAA (0.71) | GAAKDM4EPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639770-A | SUPEROXIDE INHIBITOR | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0600092-A1 | THIAZOLE DERIVATIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-08 | — | — | EP | disclosed |