SCHEMBL8925447

SCHEMBL8925447

CC=CC=COC=CCCCC

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33
LPAR2 Q9HBW0 2/20 0.32
LPAR3 Q9UBY5 2/20 0.32
LPAR1 Q92633 1/20 0.32
F7 P08709 1/20 0.31
F3 P13726 1/20 0.31
FAAH O00519 2/20 0.31
TRPV1 Q8NER1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8927083 0.94 ALDH1A1 (0.41) TSHRALDH1A1LPAR3FAAHTRPV1
SCHEMBL8927370 0.91 TSHR (0.42) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL8927352 0.86
SCHEMBL8926570 0.86 TSHR (0.45) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL1974312 0.86 TSHR (0.41) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL26094193 0.86 TSHR (0.41) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL19481 0.86 TSHR (0.41) TSHRALDH1A1LPAR2LPAR3LPAR1
SCHEMBL8926544 0.85 ALDH1A1 (0.50) TSHRALDH1A1FAAHTRPV1
Water SCHEMBL28150217 0.84 TSHR (0.39) TSHRALDH1A1LPAR2LPAR3LPAR1
Fluoride SCHEMBL27823523 0.84 TSHR (0.39) TSHRALDH1A1LPAR2LPAR3LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5600034-A HEAT TREATING DIALLYL ETHERS IN PRESENCE OF CATALYST CONTAINING PALLADIUM AND PHOSPHORUS COMPOUNDS MITSUBISHI CHEMICAL CORPORATION (JP) 1997-02-04 US disclosed