Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL28146838 | 0.82 | TSHR (0.64) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15845079 | 0.82 | ALDH1A1 (0.50) | TSHRALDH1A1 | |
| SCHEMBL20548 | 0.82 | — | — | |
| Hexane SCHEMBL11134445 | 0.77 | — | — | |
| SCHEMBL22445028 | 0.77 | — | — | |
| Hexane SCHEMBL11235960 | 0.77 | TSHR (0.70) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL6767991 | 0.77 | — | — | |
| Hexane SCHEMBL19638866 | 0.77 | TSHR (0.70) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| Hexane SCHEMBL1849323 | 0.77 | TSHR (0.70) | TSHRTHRBSMN1; SMN2LMNAALDH1A1 | |
| Hexane SCHEMBL120113 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663450-A | PROMOTES HEALING | CV THERAPEUTICS (US) | 1997-09-02 | — | — | US | disclosed |