Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 10/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | GFPT1 | Q06210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10394952 | 1.00 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL26367055 | 0.91 | HCAR2 (0.61) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL10394955 | 0.91 | HCAR2 (0.61) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL17305549 | 0.91 | HCAR2 (0.40) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL15801602 | 0.91 | HCAR2 (0.40) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL10394953 | 0.91 | HCAR2 (0.61) | HCAR2KEAP1NFE2L2ATMMAPT | |
| SCHEMBL5001830 | 0.87 | — | — | |
| SCHEMBL5001828 | 0.87 | — | — | |
| SCHEMBL5555666 | 0.82 | HCAR2 (0.33) | HCAR2KEAP1NFE2L2ATM | |
| SCHEMBL4575905 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9255622-A | — | — | None | — | — | JP | disclosed |
| JP-H09255622-A | PRODUCTION OF WATER-SOLUBLE FUMARIC ACID DIESTER | NOF CORP | 1997-09-30 | — | — | JP | disclosed |