Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.35 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924193 | 1.00 | SCN8A (0.39) | SCN8ACYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL8921414 | 0.87 | HPGD (0.32) | HRH1CYP3A4CYP2D6CYP2C9RXFP3 | |
| SCHEMBL8921400 | 0.87 | HPGD (0.32) | HRH1CYP3A4CYP2D6CYP2C9RXFP3 | |
| SCHEMBL8923728 | 0.81 | SCN8A (0.37) | SCN8ATDP1HRH1CYP3A4CYP2D6 | |
| SCHEMBL9092884 | 0.78 | HPGD (0.30) | — | |
| SCHEMBL8824474 | 0.78 | HPGD (0.32) | — | |
| SCHEMBL8824485 | 0.78 | HPGD (0.32) | — | |
| SCHEMBL8824447 | 0.77 | HPGD (0.39) | — | |
| SCHEMBL8924199 | 0.75 | SCN8A (0.46) | SCN8ACYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL8662072 | 0.75 | HPGD (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |