Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.40 |
| ▸ | PTAFR | P25105 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8921403 | 0.85 | RAB9A (0.40) | L3MBTL1HRH1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL7294953 | 0.81 | GAA (0.56) | CYP2A6TDP1L3MBTL1HRH1KMT2A | |
| SCHEMBL8923732 | 0.79 | SCN8A (0.43) | SCN8AHRH1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8923501 | 0.76 | SCN8A (0.49) | SCN8ACYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL9089532 | 0.75 | PARP15 (0.36) | L3MBTL1KMT2A | |
| SCHEMBL8924193 | 0.75 | SCN8A (0.39) | SCN8ACYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL8925846 | 0.75 | SCN8A (0.39) | SCN8ACYP2A6TDP1L3MBTL1HRH1 | |
| SCHEMBL8824453 | 0.74 | GAA (0.36) | L3MBTL1KMT2A | |
| SCHEMBL8824463 | 0.74 | MAPT (0.40) | TDP1L3MBTL1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL8558817 | 0.74 | GAA (0.35) | L3MBTL1KMT2ACYP3A4CYP2D6F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |