Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11074528 | 0.85 | KCNN4 (0.51) | MAPTKMT2AHIF1AKCNN4CYP2C19 | |
| SCHEMBL4666868 | 0.82 | MAPK1 (0.46) | MAPTKMT2AHIF1AKCNN4CYP2C19 | |
| SCHEMBL10816553 | 0.76 | KCNN4 (0.42) | MAPTKMT2AHIF1AKCNN4CYP2C19 | |
| SCHEMBL5322819 | 0.76 | KCNN4 (0.42) | MAPTKMT2AHIF1AKCNN4CYP2C19 | |
| SCHEMBL8407811 | 0.73 | KCNN4 (0.40) | MAPTKMT2AHIF1AKCNN4CYP2C19 | |
| SCHEMBL6916221 | 0.70 | CES1 (0.50) | MAPTKMT2AHIF1AKCNN4CYP2C19 | |
| SCHEMBL10444295 | 0.70 | KMT2A (0.39) | MAPTKMT2AHIF1AKCNN4CYP2C19 | |
| SCHEMBL10878702 | 0.70 | MAPT (0.47) | MAPTKMT2AHIF1AKCNN4CYP2C19 | |
| SCHEMBL13770004 | 0.70 | MAPT (0.50) | MAPTKMT2AHIF1AKCNN4CYP2C19 | |
| SCHEMBL14292070 | 0.70 | MAPK1 (0.46) | MAPTKMT2AHIF1AKCNN4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602267-A | Organometallic catalysts for epoxidizing prochiral olefins and a new class of amid-salicylidene ligands | HOECHST CELANESE (US) | 1997-02-11 | — | — | US | disclosed |
| US-5508458-A | USEFUL IN EPOXIDATION OF OLEFINS | HOECHST CELANESE CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| US-5491266-A | REACTING CHIRAL COMPOUND IN PRESENCE OF OPTICALLY ACTIVE METAL-LIGAND COMPLEX | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1996-02-13 | — | — | US | disclosed |
| EP-0600020-B1 | ASYMMETRIC SYNTHESES | UNION CARBIDE CHEM PLASTIC (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5360938-A | Metal ligand complex phosphite hydrogenation catalysts | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1994-11-01 | — | — | US | disclosed |