Aminopyrene

Aminopyrene

SCHEMBL8926014

Nc1ccc2ccc3cccc4ccc1c2c34.P

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.52
HPGD P15428 8/20 0.52
HSD17B10 Q99714 6/20 0.52
CYP3A4 P08684 5/20 0.52
CYP1A2 P05177 5/20 0.52
TSHR P16473 4/20 0.52
CYP1A1 P04798 1/20 0.52
CYP1B1 Q16678 1/20 0.52
TDP1 Q9NUW8 3/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
ERBB2 P04626 1/20 0.48
FYN P06241 1/20 0.48
MAOA P21397 1/20 0.48
ACHE P22303 1/20 0.48
AHR P35869 1/20 0.48
THRB P10828 2/20 0.48
KEAP1 Q14145 2/20 0.46
CRHBP P24387 1/20 0.45
CRHR2 Q13324 1/20 0.45
NFE2L2 Q16236 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminopyrene SCHEMBL28317542 0.98 ALDH1A1 (0.55) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2
Aminopyrene SCHEMBL29407518 0.98 ALDH1A1 (0.55) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2
Aminopyrene SCHEMBL283221 0.98 ALDH1A1 (0.55) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2
Aminopyrene SCHEMBL29360008 0.98 ALDH1A1 (0.55) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2
Aminopyrene SCHEMBL30662013 0.95 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2
Aminopyrene SCHEMBL28046803 0.95 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2
Aminopyrene SCHEMBL8926022 0.95 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2
Aminopyrene SCHEMBL27820411 0.95 ALDH1A1 (0.52) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2
Aminopyrene SCHEMBL27815195 0.93 ALDH1A1 (0.50) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2
Aminopyrene SCHEMBL28262325 0.91 ALDH1A1 (0.48) ALDH1A1HPGDHSD17B10CYP3A4CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109592962-A A kind of bionical ternary system graphene-black phosphorus nanocomposite films preparation method 北京航空航天大学 2019-04-09 CN claimed
CN-109592962-B Preparation method of bionic ternary system graphene-black phosphorus nanocomposite film 北京航空航天大学 2020-08-04 CN disclosed
CN-109592962-A A kind of bionical ternary system graphene-black phosphorus nanocomposite films preparation method 北京航空航天大学 2019-04-09 CN disclosed
US-5616805-A USING A PYRENYLAMINE COMPOUND CONTAINING AN ALDEHYDE GROUP AS CHEMICAL INTERMEDIATE RICOH COMPANY, LTD. (JP) 1997-04-01 US disclosed
US-5459275-A Photoconductive layer on electroconductive substrate; electrography; durability, heat resistance, shockproof, flexibility RICOH COMPANY, LTD. (JP) 1995-10-17 US disclosed