Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TOP2A | P11388 | 4/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522302 | 0.88 | ALDH1A1 (0.62) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9382132 | 0.88 | KCNH2 (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9386571 | 0.88 | KCNH2 (0.64) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9382881 | 0.88 | KCNH2 (0.64) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9383075 | 0.88 | KCNH2 (0.64) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10485368 | 0.88 | KCNH2 (0.64) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9383100 | 0.87 | KCNH2 (0.63) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9383106 | 0.87 | KCNH2 (0.63) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL9384134 | 0.87 | KCNH2 (0.63) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9127826 | 0.86 | ALDH1A1 (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631256-A | IMPROVED POTENCY, BROADER SPECTRUM | THE PROCTER & GAMBLE COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5328908-A | Antimicrobial quinolone thioureas | PROCTER & GAMBLE PHARMACEUTICALS, INC. (US) | 1994-07-12 | — | — | US | disclosed |
| EP-0593457-A1 | ANTIMICROBIAL QUINOLONE THIOUREAS | Norwich-Eaton Pharmaceuticals, Inc. (US) | 1994-04-27 | — | — | EP | disclosed |
| EP-0593457-A4 | ANTIMICROBIAL QUINOLONE THIOUREAS. | NORWICH EATON PHARMA (US) | 1993-01-15 | — | — | EP | disclosed |
| WO-1991016310-A1 | ANTIMICROBIAL QUINOLONE THIOUREAS | NORWICH-EATON PHARMACEUTICALS, INC. (US) | 1991-10-31 | — | — | WO | disclosed |