Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 20/20 | 0.71 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.49 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.49 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.49 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.49 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.49 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.49 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.49 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.49 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.49 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.49 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924635 | 0.91 | PLA2G2A (0.66) | PLA2G2APLA2G1B | |
| SCHEMBL8926125 | 0.89 | PLA2G2A (0.70) | PLA2G2APLA2G10PLA2G6PLA2G1BPLA2G5 | |
| SCHEMBL8926033 | 0.88 | PLA2G2A (0.70) | PLA2G2A | |
| SCHEMBL8502374 | 0.84 | PLA2G2A (0.72) | PLA2G2APLA2G10PLA2G6PLA2G1BPLA2G5 | |
| SCHEMBL7964020 | 0.83 | PLA2G2A (1.00) | PLA2G2A | |
| SCHEMBL8924652 | 0.82 | PLA2G2A (0.69) | PLA2G2APLA2G1B | |
| SCHEMBL7964245 | 0.82 | PLA2G2A (0.74) | PLA2G2A | |
| SCHEMBL8926210 | 0.80 | PLA2G2A (0.68) | PLA2G2APLA2G10PLA2G1BPLA2G5PLA2G2F | |
| SCHEMBL7964280 | 0.80 | PLA2G2A (0.85) | PLA2G2APLA2G10PLA2G6PLA2G1BPLA2G5 | |
| SCHEMBL8926129 | 0.79 | PLA2G2A (0.80) | PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684034-A | INHIBITORS OF HUMAN NON-PANCREATIC SECRETORY PHOSPHOLIPASE A2, TREATMENT OF SEPTIC SHOCK, TRAUMA, RESPIRATORY DISORDERS, RHEUMATIC ARTHRITIS, INHIBITORS OF ARACHIDONIC ACID RELEASE | ELI LILLY AND COMPANY (US) | 1997-11-04 | — | — | US | disclosed |