Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27562843 | 1.00 | TSHR (0.61) | TSHRSMN1; SMN2CTSKCA2MAPK1 | |
| SCHEMBL8072555 | 0.79 | ALDH1A1 (0.56) | TSHRSMN1; SMN2CA2MAPK1 | |
| SCHEMBL8072556 | 0.79 | ALDH1A1 (0.56) | TSHRSMN1; SMN2CA2MAPK1 | |
| SCHEMBL6554564 | 0.78 | — | — | |
| SCHEMBL366897 | 0.78 | — | — | |
| SCHEMBL366896 | 0.78 | — | — | |
| SCHEMBL5470583 | 0.78 | — | — | |
| SCHEMBL15760 | 0.78 | — | — | |
| SCHEMBL9466751 | 0.78 | — | — | |
| SCHEMBL1188285 | 0.78 | TSHR (0.55) | TSHRSMN1; SMN2CTSKCA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684215-A | CATALYTIC REDUCTION OF ALDEHYDES OR KETONES WITH HYDROGEN IN THE PRESENCE OF NICKEL ON ALUMINA AND ZIRCONIA | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |