SCHEMBL8926359

SCHEMBL8926359

C=CCOCC(O)CSC(CC(=O)O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.45
CA2 P00918 5/20 0.45
CA7 P43166 4/20 0.45
CPB1 P15086 1/20 0.36
CYP2C19 P33261 2/20 0.35
CA9 Q16790 4/20 0.34
CA4 P22748 3/20 0.34
ALDH1A1 P00352 2/20 0.33
POLB P06746 2/20 0.33
CYP2C9 P11712 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPSR1 Q6W5P4 1/20 0.32
SLC22A6 Q4U2R8 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4443728 0.82 CA1 (0.59) CA1CA2CA7CA9CA4
SCHEMBL6424785 0.74 CA1 (0.63) CA1CA2CA7CA9CA4
SCHEMBL8926368 0.74 CA1 (0.46) CA1CA2CA7CYP2C19CA9
SCHEMBL8927018 0.74 CA1 (0.46) CA1CA2CA7CA9CA4
SCHEMBL8926354 0.72 CA1 (0.47) CA1CA2CA7CA9CA4
SCHEMBL1968820 0.71 CA1 (0.50) CA1CA2CA7CA9CA4
SCHEMBL8979305 0.71 CPB1 (0.44) CPB1CYP2C19ALDH1A1POLBCYP2C9
SCHEMBL7619922 0.71 CA1 (0.44) CA1CA2CA7CA9CA4
SCHEMBL8926362 0.71 CA1 (0.46) CA1CA2CA7CA9CA4
SCHEMBL18604307 0.70 CA1 (0.52) CA1CA2CA7CA9CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5614181-A Nonionic surfactants derived from 1,2-isopropylidene-3-epoxypropylglycerol and a carboxylic acid and their use L'OREAL (FR) 1997-03-25 US disclosed