Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.51 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | F7 | P08709 | 4/20 | 0.50 |
| ▸ | F3 | P13726 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8926366 | 1.00 | PDE5A (0.67) | PDE5APOLBMEN1KMT2ASOAT2 | |
| SCHEMBL7753510 | 0.98 | PDE5A (0.69) | PDE5APOLBMEN1KMT2ASOAT2 | |
| SCHEMBL7961322 | 0.98 | PDE5A (0.69) | PDE5APOLBMEN1KMT2ASOAT2 | |
| SCHEMBL7971549 | 0.98 | PDE5A (0.69) | PDE5APOLBMEN1KMT2ASOAT2 | |
| SCHEMBL7753522 | 0.98 | PDE5A (0.69) | PDE5APOLBMEN1KMT2ASOAT2 | |
| SCHEMBL7757262 | 0.98 | PDE5A (0.69) | PDE5APOLBMEN1KMT2ASOAT2 | |
| SCHEMBL7759510 | 0.98 | PDE5A (0.69) | PDE5APOLBMEN1KMT2ASOAT2 | |
| SCHEMBL7961319 | 0.98 | PDE5A (0.69) | PDE5APOLBMEN1KMT2ASOAT2 | |
| SCHEMBL7753534 | 0.98 | PDE5A (0.69) | PDE5APOLBMEN1KMT2ASOAT2 | |
| SCHEMBL7971544 | 0.98 | PDE5A (0.69) | PDE5APOLBMEN1KMT2ASOAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688821-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, SKIN DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-18 | — | — | US | claimed |
| US-5688821-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS, SKIN DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |