Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254908 | 0.93 | POLB (0.36) | NPC1JAK2RAB9APAX8SIGMAR1 | |
| SCHEMBL2380256 | 0.80 | EGFR (0.40) | CSNK1ENPC1JAK2RAB9APAX8 | |
| SCHEMBL4194245 | 0.79 | CSNK1E (0.44) | CSNK1ENPC1JAK2RAB9APAX8 | |
| SCHEMBL17440485 | 0.78 | SIGMAR1 (0.46) | CSNK1ENPC1JAK2RAB9APAX8 | |
| SCHEMBL28546510 | 0.78 | SIGMAR1 (0.46) | CSNK1ENPC1JAK2RAB9APAX8 | |
| SCHEMBL29025317 | 0.78 | SIGMAR1 (0.46) | CSNK1ENPC1JAK2RAB9APAX8 | |
| SCHEMBL28543069 | 0.78 | SIGMAR1 (0.46) | CSNK1ENPC1JAK2RAB9APAX8 | |
| SCHEMBL2493913 | 0.76 | CSNK1E (0.41) | CSNK1ENPC1JAK2RAB9APAX8 | |
| SCHEMBL571119 | 0.76 | CSNK1E (0.41) | CSNK1ENPC1JAK2RAB9APAX8 | |
| SCHEMBL17440484 | 0.76 | SIGMAR1 (0.44) | CSNK1ENPC1JAK2RAB9APAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614124-A | OILS WITH ANTIOXIDANT-DISPERSANTS OF POLYOLEFIN SUCCINIMIDE AND PHENOTHIAZINE | ETHYL ADDITIVES CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |