Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.74 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.66 |
| ▸ | PPIA | P62937 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646955 | 0.89 | BRD4 (0.74) | BRD4CYP19A1PPIAMEN1KMT2A | |
| SCHEMBL8924076 | 0.86 | BRD4 (1.00) | BRD4CYP19A1PPIAMEN1KMT2A | |
| SCHEMBL10601802 | 0.85 | BRD4 (0.72) | BRD4CYP19A1MEN1KMT2AKDM4E | |
| SCHEMBL9732666 | 0.85 | BRD4 (0.72) | BRD4CYP19A1MEN1KMT2A | |
| SCHEMBL5399487 | 0.84 | BRD4 (0.70) | BRD4CYP19A1MEN1KMT2A | |
| SCHEMBL11959269 | 0.82 | BRD4 (0.68) | BRD4CYP19A1MEN1KMT2AKDM4E | |
| SCHEMBL11959273 | 0.82 | BRD4 (0.68) | BRD4CYP19A1MEN1KMT2AKDM4E | |
| SCHEMBL9197891 | 0.82 | PKM (0.54) | BRD4CYP19A1KMT2AKDM4ELMNA | |
| SCHEMBL14200019 | 0.82 | BRD4 (0.67) | BRD4CYP19A1MEN1KMT2ALMNA | |
| SCHEMBL11959268 | 0.82 | BRD4 (0.76) | BRD4CYP19A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5639906-A | Fluorescent and NMR sensitive pH indicators | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1997-06-17 | — | — | US | disclosed |