⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166980 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL2773491 | 0.97 | — | — | |
| SCHEMBL538846 | 0.88 | — | — | |
| SCHEMBL9387320 | 0.88 | — | — | |
| SCHEMBL176076 | 0.86 | EPHX1 (0.39) | — | |
| SCHEMBL10482352 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL4416986 | 0.84 | KDM4E (0.38) | — | |
| Hydrochloric Acid SCHEMBL4409590 | 0.84 | KDM4E (0.38) | — | |
| SCHEMBL7859411 | 0.82 | — | — | |
| SCHEMBL4019377 | 0.82 | DPP4 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210395185-A1 | SCALABLE SYNTHESIS OF OPTICALLY ACTIVE 1-CYCLOPROPYLALKYL-1-AMINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2021-12-23 | — | — | US | claimed |
| WO-2020079145-A1 | SCALABLE SYNTHESIS OF OPTICALLY ACTIVE 1-CYCLOPROPYLALKYL-1-AMINES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-04-23 | — | — | WO | claimed |
| CN-111434665-B | Ensultamidenamide-arylamide compounds and their use for treating hepatitis B | 上海长森药业有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-113286798-A | Ensultiamidinamide-aryl amide compound and application thereof in treating hepatitis B | 上海长森药业有限公司 | 2021-08-20 | — | — | CN | disclosed |
| CN-111434665-A | Ensultiamidinamide-aryl amide compound and application thereof in treating hepatitis B | 上海长森药业有限公司 | 2020-07-21 | — | — | CN | disclosed |
| CN-110520406-A | Cyclopropyl pheynylalkylamine and preparation method thereof | BOEHRINGER INGELHEIM INT | 2019-11-29 | — | — | CN | disclosed |
| US-8431569-B2 | Inhibitors of janus kinases | MERCK SHARP & DOHME CORP. (US) | 2013-04-30 | — | — | US | disclosed |
| US-8431569-B2 | Inhibitors of janus kinases | MERCK SHARP & DOHME CORP. (US) | 2013-04-30 | — | — | US | disclosed |
| US-20100267709-A1 | INHIBITORS OF JANUS KINASES | MERCK SHARP & DOHME LLC | 2010-10-21 | — | — | US | disclosed |
| US-5621142-A | N-METHYLASPARATIC ACID ANTAGONIST | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5621142-A | N-METHYLASPARATIC ACID ANTAGONIST | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-04-15 | — | — | US | disclosed |
| US-5621142-A | N-METHYLASPARATIC ACID ANTAGONIST | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-04-15 | — | — | US | disclosed |
| EP-0747348-A1 | AMINOALKYLCYCLOPROPANE DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1996-12-11 | — | — | EP | disclosed |
| EP-0747348-A1 | AMINOALKYLCYCLOPROPANE DERIVATIVE | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1996-12-11 | — | — | EP | disclosed |
| CN-1079745-A | New 9-fluoro-7-oxo-7H-pyrido [1,2,3-d, e] [1,4] benzoxazine-6-carboxylic acids and ester thereof | BAYER AG (DE) | 1993-12-22 | — | — | CN | disclosed |
| EP-0563734-A1 | 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents | BAYER AG (DE) | 1993-10-06 | — | — | EP | disclosed |