Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.55 |
| ▸ | F10 | P00742 | 8/20 | 0.55 |
| ▸ | ST14 | Q9Y5Y6 | 6/20 | 0.55 |
| ▸ | PLG | P00747 | 6/20 | 0.55 |
| ▸ | PLAU | P00749 | 6/20 | 0.55 |
| ▸ | HPN | P05981 | 1/20 | 0.51 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927592 | 0.90 | F2 (0.57) | F2F10ST14PLGPLAU | |
| SCHEMBL8926165 | 0.88 | F2 (0.51) | F2F10ST14PLGPLAU | |
| SCHEMBL8927390 | 0.87 | F2 (0.54) | F2F10ST14PLGPLAU | |
| SCHEMBL8927588 | 0.85 | F2 (0.56) | F2F10ST14PLGPLAU | |
| Hydrochloric Acid SCHEMBL8947724 | 0.84 | F2 (0.59) | F2F10ST14PLGPLAU | |
| SCHEMBL8947777 | 0.84 | F2 (0.59) | F2F10ST14PLGPLAU | |
| SCHEMBL7304953 | 0.81 | F2 (0.51) | F2F10ST14PLGPLAU | |
| Hydrochloric Acid SCHEMBL8947713 | 0.81 | F2 (0.51) | F2F10ST14PLGPLAU | |
| SCHEMBL8947796 | 0.81 | F2 (0.63) | F2 | |
| SCHEMBL8947725 | 0.80 | F2 (0.63) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |