Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 17/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.52 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927390 | 0.96 | F2 (0.54) | F2F10PLGPLAUST14 | |
| SCHEMBL8927592 | 0.91 | F2 (0.57) | F2F10PLGPLAUST14 | |
| SCHEMBL8926899 | 0.85 | F2 (0.55) | F2F10PLGPLAUST14 | |
| SCHEMBL8926165 | 0.84 | F2 (0.51) | F2F10PLGPLAUST14 | |
| SCHEMBL8947796 | 0.80 | F2 (0.63) | F2 | |
| SCHEMBL8947770 | 0.80 | F2 (0.63) | F2 | |
| Hydrochloric Acid SCHEMBL8947751 | 0.79 | F2 (0.64) | F2 | |
| SCHEMBL8947725 | 0.79 | F2 (0.63) | F2 | |
| SCHEMBL7306679 | 0.79 | F2 (0.52) | F2F10PLG | |
| SCHEMBL8719586 | 0.79 | F2 (0.53) | F2F10PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677448-A | CHEMICAL INTERMEDIATES FOR MAKING ANTAGONIST OF THROMBIN, TREATING THROMBOSIS, STROKE, INFLAMMATION, ARTERIOSCLEROSIS, CARDIOVASCULAR DISORDERS | HOFFMANN-LA ROCHE INC. (US) | 1997-10-14 | — | — | US | disclosed |