Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924421 | 0.92 | PLA2G2A (0.71) | PLA2G2APLA2G1B | |
| SCHEMBL8924862 | 0.86 | PLA2G2A (0.69) | PLA2G2A | |
| SCHEMBL8925313 | 0.86 | PLA2G2A (0.71) | PLA2G2APLA2G1B | |
| SCHEMBL8924924 | 0.86 | PLA2G2A (0.74) | PLA2G2APLA2G1B | |
| SCHEMBL8926192 | 0.84 | PLA2G2A (0.71) | PLA2G2A | |
| SCHEMBL7953243 | 0.83 | PLA2G2A (1.00) | PLA2G2APLA2G1B | |
| SCHEMBL24353497 | 0.82 | PLA2G2A (0.85) | PLA2G2A | |
| SCHEMBL7963213 | 0.80 | PLA2G2A (0.82) | PLA2G2APLA2G1B | |
| SCHEMBL8924932 | 0.80 | PLA2G2A (0.70) | PLA2G2APLA2G1B | |
| SCHEMBL8924954 | 0.80 | PLA2G2A (0.80) | PLA2G2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684034-A | INHIBITORS OF HUMAN NON-PANCREATIC SECRETORY PHOSPHOLIPASE A2, TREATMENT OF SEPTIC SHOCK, TRAUMA, RESPIRATORY DISORDERS, RHEUMATIC ARTHRITIS, INHIBITORS OF ARACHIDONIC ACID RELEASE | ELI LILLY AND COMPANY (US) | 1997-11-04 | — | — | US | disclosed |