Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.30 |
| ▸ | G6PD | P11413 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927036 | 0.91 | SRD5A2 (0.33) | SRD5A2ARKCNH2G6PD | |
| SCHEMBL8926995 | 0.90 | SRD5A2 (0.33) | SRD5A2ARKCNH2G6PD | |
| SCHEMBL8927172 | 0.90 | SRD5A2 (0.33) | SRD5A2ARKCNH2 | |
| SCHEMBL8926912 | 0.88 | SRD5A2 (0.34) | SRD5A2ARKCNH2 | |
| SCHEMBL8926900 | 0.87 | SRD5A2 (0.34) | SRD5A2ARKCNH2G6PD | |
| SCHEMBL9113792 | 0.86 | GPBAR1 (0.36) | SRD5A2SRD5A1 | |
| SCHEMBL8926954 | 0.85 | SRD5A1 (0.36) | SRD5A2ARKCNH2SRD5A1 | |
| SCHEMBL8926814 | 0.85 | SRD5A2 (0.33) | SRD5A2ARKCNH2 | |
| SCHEMBL8927029 | 0.84 | G6PD (0.34) | ARG6PD | |
| SCHEMBL8926272 | 0.83 | NR1H4 (0.37) | SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |