Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8927169 | 0.89 | G6PD (0.36) | SRD5A2ARKCNH2 | |
| SCHEMBL8927275 | 0.86 | AR (0.37) | SRD5A2ARKCNH2 | |
| SCHEMBL8926946 | 0.85 | ESR1 (0.33) | SRD5A2ARKCNH2 | |
| SCHEMBL8926912 | 0.82 | SRD5A2 (0.34) | SRD5A2ARKCNH2 | |
| SCHEMBL8924896 | 0.81 | AR (0.35) | SRD5A2ARKCNH2CYP19A1 | |
| SCHEMBL8926900 | 0.81 | SRD5A2 (0.34) | SRD5A2ARKCNH2 | |
| SCHEMBL8927180 | 0.81 | AR (0.36) | SRD5A2ARKCNH2 | |
| SCHEMBL8927172 | 0.80 | SRD5A2 (0.33) | SRD5A2ARKCNH2 | |
| SCHEMBL8927036 | 0.80 | SRD5A2 (0.33) | SRD5A2ARKCNH2 | |
| SCHEMBL8926814 | 0.80 | SRD5A2 (0.33) | SRD5A2ARKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693809-A | PREGNANES FOR TREATING ALOPECIA, ACNE AND SKIN DISORDER | MERCK & CO., INC. (US) | 1997-12-02 | — | — | US | disclosed |