Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.84 |
| ▸ | MEN1 | O00255 | 2/20 | 0.84 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15480415 | 0.84 | MEN1 (0.84) | KMT2AMEN1HTTHDAC1HDAC3 | |
| SCHEMBL29152068 | 0.82 | MEN1 (0.56) | KMT2AMEN1HDAC1HDAC3HDAC2 | |
| SCHEMBL5456482 | 0.81 | KMT2A (0.68) | KMT2AMEN1HTTNPC1RAB9A | |
| SCHEMBL31146466 | 0.81 | KMT2A (0.68) | KMT2AMEN1HTTNPC1RAB9A | |
| SCHEMBL29152081 | 0.81 | HDAC3 (0.57) | KMT2AMEN1HDAC1HDAC3HDAC2 | |
| SCHEMBL10499295 | 0.81 | HDAC3 (0.60) | KMT2AMEN1HDAC1HDAC3HDAC2 | |
| SCHEMBL29152061 | 0.81 | HDAC3 (0.57) | KMT2AMEN1HDAC1HDAC3HDAC2 | |
| SCHEMBL3679343 | 0.81 | MEN1 (0.55) | KMT2AMEN1HTTHDAC1HDAC3 | |
| SCHEMBL17293496 | 0.80 | CACNA1G (0.55) | KMT2AMEN1HDAC1HDAC3NPC1 | |
| SCHEMBL31695276 | 0.80 | CACNA1G (0.55) | KMT2AMEN1HDAC1HDAC3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631403-A | HYDROLYSIS OF HALOCARBOXANILIDE IN SOLVENT | HOECHST AG (DE) | 1997-05-20 | — | — | US | disclosed |