Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EDNRA | P25101 | 3/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10743994 | 0.80 | CYP2C9 (0.53) | HTTCYP2C9ALDH1A1LMNAALB | |
| SCHEMBL19002770 | 0.80 | EDNRA (0.50) | HTTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL19002773 | 0.80 | EDNRA (0.50) | HTTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL11119863 | 0.78 | HTT (0.58) | HTTCYP2C9ALDH1A1LMNAALB | |
| SCHEMBL18895700 | 0.77 | EDNRA (0.54) | LMNATSHRKMT2AEDNRAMAPT | |
| SCHEMBL18879361 | 0.77 | EDNRA (0.54) | LMNATSHRKMT2AEDNRAMAPT | |
| SCHEMBL11117907 | 0.76 | EDNRA (0.53) | ALDH1A1LMNATSHRKMT2AEDNRA | |
| SCHEMBL8926509 | 0.76 | HTT (0.59) | HTTCYP2C9ALDH1A1LMNAALB | |
| SCHEMBL14243082 | 0.74 | MAPT (0.56) | LMNATSHRKMT2AEDNRAMAPT | |
| SCHEMBL10753943 | 0.74 | CYP2C9 (0.59) | HTTCYP2C9ALDH1A1LMNAALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608143-A | NUCLEIC ACID PROMOTER FRAGMENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| US-5364780-A | Genetic engineering with DNA and promoters | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0463056-A1 | EXTERNAL REGULATION OF GENE EXPRESSION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-01-02 | — | — | EP | disclosed |
| WO-1990011361-A1 | EXTERNAL REGULATION OF GENE EXPRESSION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-10-04 | — | — | WO | disclosed |
| EP-0388186-A1 | External regulation of gene expression | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-09-19 | — | — | EP | disclosed |