SCHEMBL11117907

SCHEMBL11117907

COC(=O)c1sccc1S(=O)(=O)NC(N)=O

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EDNRA P25101 3/20 0.53
MAPT P10636 4/20 0.51
PPARG P37231 1/20 0.47
PPARD Q03181 1/20 0.47
PPARA Q07869 1/20 0.47
LMNA P02545 4/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
TP53 P04637 1/20 0.45
KCNH2 Q12809 1/20 0.45
POLB P06746 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
THRB P10828 1/20 0.44
KMT2A Q03164 2/20 0.44
CCKBR P32239 1/20 0.44
SLC10A6 Q3KNW5 1/20 0.43
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18879361 0.86 EDNRA (0.54) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL18895700 0.86 EDNRA (0.54) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL11469582 0.83 EDNRA (0.56) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL11116844 0.83 MEN1 (0.56) EDNRALMNATSHRKDM4EKMT2A
SCHEMBL4358291 0.81 CA1 (0.51) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL8427062 0.80 EDNRA (0.42) EDNRAMAPTKMT2AMEN1
SCHEMBL12319426 0.79 EDNRA (0.52) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL11471141 0.79 EDNRA (0.52) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL23569071 0.78 EDNRA (0.49) EDNRAMAPTPPARGPPARDPPARA
SCHEMBL12293575 0.78 MAPT (0.63) EDNRAMAPTPPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1487789-A Selective herbicides based on 2, 6-disubstituted pyridine derivatives 2004-04-07 CN claimed
CN-1278607-C Selective herbicides based on 2, 6-disubstituted pyridine derivatives BAYER AG (DE) 2006-10-11 CN disclosed
CN-1768582-A Selective herbicides based on 2,6-disubstituted pyridine derivatives BAYER AG (DE) 2006-05-10 CN disclosed
CN-1487789-A Selective herbicides based on 2, 6-disubstituted pyridine derivatives 2004-04-07 CN disclosed
CN-1053786-A Urea derivatives having herbicidal activity and process for producing the same NEHEZVEGYIPARI KUTATO INTEZET (HU) 1991-08-14 CN disclosed
EP-0127469-A2 Antidotes for sulfonylurea herbicides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-12-05 EP disclosed