SCHEMBL8927396

SCHEMBL8927396

CCCCCC=CC=COC=CC=CCCCCC

nearest known ligand 0.58

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.58
TSHR P16473 1/20 0.58
FASN P49327 1/20 0.50
FAAH O00519 4/20 0.44
TRPV1 Q8NER1 2/20 0.44
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8927394 1.00 ALDH1A1 (0.58) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL8927108 0.98 TSHR (0.56) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL8927112 0.98 TSHR (0.56) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL14673404 0.98 TSHR (0.56) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL14673405 0.98 TSHR (0.56) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL6684917 0.95 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL6684919 0.95 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL9017431 0.93 ALDH1A1 (0.57) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL8926884 0.93 ALDH1A1 (0.52) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL9017432 0.93 ALDH1A1 (0.57) ALDH1A1TSHRFASNFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5600034-A HEAT TREATING DIALLYL ETHERS IN PRESENCE OF CATALYST CONTAINING PALLADIUM AND PHOSPHORUS COMPOUNDS MITSUBISHI CHEMICAL CORPORATION (JP) 1997-02-04 US disclosed