Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8931114 | 0.92 | DGAT1 (0.64) | DGAT1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL8931713 | 0.92 | DGAT1 (0.64) | DGAT1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL9287329 | 0.90 | MAPT (0.64) | DGAT1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL7878336 | 0.89 | DGAT1 (0.53) | DGAT1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL8931115 | 0.89 | DGAT1 (0.63) | DGAT1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL8931655 | 0.89 | DGAT1 (0.60) | DGAT1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL8758342 | 0.87 | DGAT1 (0.61) | DGAT1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL8931747 | 0.87 | DGAT1 (0.58) | DGAT1LMNAMAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL3030510 | 0.86 | DGAT1 (0.57) | DGAT1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL13218950 | 0.85 | DGAT1 (0.59) | DGAT1LMNAMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5637592-A | TREATING HELICOBACTER INFECTIONS, SUCH AS GASTRITIS, STOMACH ULCERS, DUODENAL ULCERS AND GASTRIC CANCER | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-06-10 | — | — | US | disclosed |
| US-5607932-A | Heterocyclic derivatives of azolones | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-03-04 | — | — | US | disclosed |