Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | TSHR | P16473 | 4/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | CNR2 | P34972 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Salicylic Acid SCHEMBL8927883 | 1.00 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Salicylic Acid SCHEMBL996984 | 1.00 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Salicylic Acid SCHEMBL8927788 | 1.00 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Salicylic Acid SCHEMBL8927567 | 1.00 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Salicylic Acid SCHEMBL8927590 | 1.00 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| 2-Hydroxybenzoic Acid Hexyl Ester SCHEMBL28670575 | 1.00 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Salicylic Acid SCHEMBL31387030 | 0.99 | TSHR (0.71) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| Salicylic Acid SCHEMBL28286211 | 0.99 | TSHR (0.71) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| 2-Hydroxybenzoic Acid Butyl Ester SCHEMBL2684191 | 0.94 | TSHR (0.71) | ALDH1A1TSHRLMNACYP3A4MAPK1 | |
| SCHEMBL411474 | 0.94 | ALDH1A1 (0.81) | ALDH1A1TSHRLMNACYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633060-A | Optical disk substrate, optical disk and aromatic polycarbonate resin | TEIJIN CHEMICALS, LTD. (JP) | 1997-05-27 | — | — | US | disclosed |